Early Rule-out of AMI

copeptin-early-rule-out-of-ami-indications

In this era of overcrowded emergency departments (EDs), measuring Copeptin along with Troponin (Tn) in the first blood draw now is proven to safely increase ED discharge, and significantly decrease hospital and ED/chest pain unit (CPU) lengths-of-stay, in patients presenting with signs and symptoms of Acute Coronary Syndrome (ACS).

Copeptin – Safe AMI Rule-Out on admission with the 1st blood draw.
Now recommended in the 2015 ESC Guidelines.

Fast, accurate AMI rule-out should help:

  • Better target monitoring and interventions to the ~10% of chest pain patients truly having AMI
  • Avoid unnecessary monitoring, treatment, waits for discharge, and anxiety in the ~90% of chest pain patients without AMI Ref-1
  • Optimize resource allocation and processes at the hospital level
  • Optimize patient management in the ED
  • Improve patient risk stratification

References Rule-out AMI

Ref-1: Mockel M, Searle J, Muller R et al. Chief complaints in medical emergencies: do they relate to underlying disease and outcome? The Charite Emergency Medicine Study (CHARITEM). Eur J Emerg Med 2013; 20: 103-108 DOI: 10.1097/MEJ.0b013e328351e609

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